I/O error

HI All

Good Day

i have I\O problem with data protector backup

when start to backup  from HPUX server to PDF file size 32G

Backup LOG

[Normal] From: ###### "/INHIS02"  Time: 18/7/2013 10:16:44 AM
    STARTING Disk Agent for ####:/INHIS02 "/INHIS02".

[Minor] From:######"/INHIS02"  Time: 18/7/2013 10:21:26 AM
[81:78]      /INHIS02/oradata/inao/inrep/PPS_GLOBAL_RPT/PPS_GLOBAL_RPT_TBS102.dbf
    Cannot read 261832 bytes at offset 7434457216: ([5] I/O error).

[Warning] From:####### "/INHIS02"  Time: 18/7/2013 10:21:28 AM
    No objects backed up.

[Normal] From: ######## "/INHIS02"  Time: 18/7/2013 10:22:02 AM
    COMPLETED Disk Agent for drsrv:/INHIS02 "/INHIS02".

Any suggestion

Best Regards