Hi,
I did that the same always.
1 thing I bring into notice that, This issue occurs in DC, the same data is replicated to DR, and in DR the error never occurs,
Regarding RegEDIT of the Server, as read at the Microsoft site, the same configuration of servers are there on DC and DR, so if its the issue with Regedit then it should occur at DR too.
Regards
Srijan Sharma